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GNOMIX: An Australian Case Study to Democratise Clinical Applications of Genomics with MGI's DNBSEQ™ Platforms

Release date:2023-02-16Writer:MGIViews:428Share

BRISBANE, Australia, February 16, 2023 - GNOMIX is an Australian specialty molecular genetics laboratory and consultation service. Empowered by MGI's DNBSEQ™ platform, GNOMIX has been providing high-quality customised genetic services for national and international customers since 2020 including laboratory services, clinical trials, research projects, independent testing for commercialisation, food and agri-genomics, and consultancy to allied industries.




Currently the clinical genomics landscape in Australia is strongly influenced by a couple of major players heavily driven by profit to provide a limited number of mainstream services. This results in the lack of availability and accessibility of technology and resources for small and medium customers, and more broadly, the stagnation of technological development. The mission of GNOMIX is to fill this gap and adapt to a wider base of customers with specific sequencing needs, budget, and timeframe.


The GNOMIX laboratory located in Adelaide, South Australia, is accredited by National Association of Testing Authorities (NATA) to ISO/IEC 17025 standards for laboratory testing. The lab is equipped with a DNBSEQ-G50 Genetic Sequencer* in conjunction of a MGISP-100 Automated Sample Preparation System. Since inception, GNOMIX has supported numerous innovative projects from home and abroad including clinical trials, primary research, high-impact publications, large commercial projects and is rapidly expanding in both capacity and capability.


"GNOMIX is not aiming to compete with major pathology laboratories", Chief Scientist Dr. Scott Grist said, "We aim to fit in a niche of providing tailored and responsive services to our clients' needs. DNBSEQ-G50* accompanied by MGISP-100 liquid handling robot, makes an ideal scale for us as a start-up and has good capacity for expansion."


DNBSEQ-G50* is a compact and flexible benchtop genetic sequencer. With the design allowing a choice of two (2) different size Flow Cells, it enables high flexibility and a perfect balance between speed and affordability. The Flow Cell Small (FCS) mode allows short turnaround time, and Flow Cell Large (FCL) mode allows lower cost per sample. Coupled with flexible read length options for both FCS and FCL, DNBSEQ-G50 can support a wide range of research and clinical applications such as low-pass Whole Genome Sequencing, targeted sequencing, small Whole Genome Sequencing, RNA Sequencing and Whole Exome Sequencing, and more.




MGISP-100 Sample Preparation System is a perfect adjunct to DNBSEQ-G50 to meet small and agile sequencing needs. MGISP-100 is an automated workstation specialised in high-throughput sequencing library preparation. Integrating 8-channel pipettes, MGISP-100 can automatically process samples in batches, free the lab technician from time-consuming repetitive procedures, increase the stability of library preparation, and reduce the total operational costs, which significantly enhances the overall efficiency in the laboratory.




Throughout the COVID pandemic, GNOMIX has expanded its client base and gained strong foothold in the national sequencing arena with initial outreach to international markets. "DNBSEQ-50* has just the right starting scale for small experiments for the start-up stage." Dr. Grist said, "As we expand our business into the next stage, we are also looking at acquiring a DNBSEQ-G400 instrument*."


Empowered by the proprietary technology DNBSEQ™, MGI provides a suite of genetic sequencers ranging from small and medium, high and ultra-high throughput to suit different sequencing applications, including DNBSEQ-G50*, DNBSEQ-G99*, DNBSEQ-G400*, DNBSEQ-T7*, DNBSEQ-T20×2RS* and more.


Australia is a well-established player in the global medical genetics field and is recognised a global and regional hub for biomedical innovation. Sharing the MGI's vision of enabling people to live better and healthier lives, GNOMIX is committed to contributing to the development of precision health in Australia and internationally.


However, the current industry bottleneck remains that many innovative biomedical research organisations and biotech companies do not have the access to the resources or capabilities to support their research and development.


"I think the industry needs to move away from the tendency towards large facilities. Large facilities have evolved for economic purposes, but they have been quite poor at providing timely services." Dr. Grist said, "My view is that we need to democratise genomics services. What I mean by that is that we need them to be more broadly based and more accessible."


About Gnomix

GNOMIX Pty Ltd, based in Adelaide, South Australia, is a privately owned laboratory providing Molecular Genetic services to the Local, National and International Scientific communities.  GNOMIX strives to use the best technology and our unparalleled experience to provide high quality molecular laboratory and consultancy services, which are individually designed to customer needs. GNOMIX practices the highest standards of quality control and is accredited to ISO/IEC 17025 standard for laboratories. For mor information please visit our website or connect with us on Twitter or LinkedIn


GNOMIX Media Contact: Scott Grist, GNOMIX Pty Ltd, admin@gnomix.com.au


About MGI

MGI Tech Co. Ltd. (MGI), headquartered in Shenzhen, is committed to building core tools and technology to lead life science through intelligent innovation. Based on its proprietary technology, MGI focuses on research & development, production and sales of sequencing instruments, reagents, and related products to support life science research, agriculture, precision medicine and healthcare. MGI is a leading producer of clinical high-throughput gene sequencers*, and its multi-omics platforms include genetic sequencing*, medical imaging, and laboratory automation. MGI's mission is to develop and promote advanced life science tools for future healthcare. For more information, please visit MGI website or connect with us on TwitterLinkedIn or YouTube.


Unless otherwise informed, StandardMPS and CoolMPS sequencing reagents, and sequencers for use with such reagents are not available in Germany, Spain, UK, Sweden, Belgium, Italy, Finland, Czech Republic, Switzerland, Portugal, Austria and Romania. Unless otherwise informed, StandardMPS sequencing reagents, and sequencers for use with such reagents are not available in Hong Kong.


MGI Media Contact: Stephanie Sun, MGI Australia  stephaniesun@mgi-tech.com

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