In October this year, the "Million Microbiome of Humans Project“ (MMHP) was officially launched at the 14th International Conference on Genomics (ICG-14) in Shenzhen. At that time, we interviewed key representatives of the project, including Lars Engstrand, professor at the Center for Microbial Translational Research at the Karolinska Institutet and Liu Ruixin, researcher at the Shanghai National Clinical Research Center for Metabolic Diseases. Recently, MGI officially opened a new R&D and manufacturing facility in Riga, Latvia, aiming to build a bridge between China and Europe for health science innovation. MMHP as a key component is also planning to conduct research work in the facility. We will combine the contents of the speeches and interviews in the two activities to further understand the "Million Microbiome of Humans Project“ (MMHP).