MGI Platform Publications

2019-06-13

	species	Publications	Journal Title	IF	Year	Techology
1	Leaf armor	Comparative transcriptome analysis of chemosensory genes in two sister leaf beetles provides insights into chemosensory speciation	Insect Biochemistry and Molecular Biology	3.756	2016	RNA-Seq
2	human	cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs	Clinical Epigenetics	4.987	2016	Small RNA
3	human	Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype	Oncotarget	5.168	2017	RNA-Seq
4	human	Overexpression of placenta specific 8 is associated with malignant progression and poor prognosis of clear cell renal cell carcinoma	International Urology and Nephrology	1.564	2017	RNA-Seq
5	Rice	Overexpression of OsHSP18.0-CI Enhances Resistance to Bacterial Leaf Streak in Rice	Rice	3.739	2017	RNA-Seq
6	Klebsiella	Coordination of metabolic pathways: Enhanced carbon conservation in 1,3-propanediol production by coupling with optically pure lactate biosynthesis	Metabolic Engineering	8.142	2017	RNA-Seq
7	human	A reference human genome dataset of the BGISEQ-500 sequencer	GigaScience	7.267	2017	WGS
8	Rhodiola crenulata	Draft genome sequence of the Tibetan medicinal herb, Rhodiola crenulata	GigaScience	7.267	2017	RNA-Seq
9	Drosophila	Drug induces depression-like phenotypes and alters gene expression profiles in Drosophila	Brain Research Bulletin	3.033	2017	RNA-Seq
10	Dog&wolf	Comparative performance of the BGISEQ-500 versus Illumina HiSeq2500 sequencing platforms for palaeogenomic sequencing	GigaScience	7.267	2017	WGS
11	human	Recessive mutation in EXOSC3 associates with mitochondrial dysfunction and pontocerebellar hypoplasia	Mitochondrion	3.704	2017	RNA-Seq
12	oilseed rape	Genome-scale mRNA transcriptomic insights into the responses of oilseed rape (Brassica napus L.) to varying boron availabilities	Plant and Soil	3.052	2017	RNA-Seq
13	Mouse	Nuclear carbonic anhydrase 6B associates with PRMT5 to epigenetically promote IL-12 expression in innate response	PNAS	9.661	2017	RNA-Seq&ChIP-Seq
14	human	Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity	Cell	30.41	2017	RNA-Seq
15	Arabidopsis thaliana	AtACS8 plays a critical role in the early biosynthesis of ethylene elicited by copper ions in Arabidopsis	Journal of Cell Science	4.431	2017	RNA-Seq
16	human	The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer	The Journal of Clinical Investigation	12.784	2017	ChIP-Seq
17	Amphioxus	Transcriptome-wide analysis of immune-responsive microRNAs against poly (I:C) challenge in Branchiostoma belcheri by deep sequencing and bioinformatics	Oncotarget	5.168	2017	Small RNA
18	human	PBRM1 restricts the basal activity of innate immune system through repressing RIG-I-like receptor signaling and is a potential prognostic biomarker for colon cancer	The Journal of Pathology	6.894	2017	RNA-Seq
19	Amphioxus	Exploring gene expression changes in the amphioxus gill after poly(I:C) challenge using digital expression profiling	Fish & Shellfish Immunology	3.148	2017	RNA-Seq
20	Sea cucumber	Genome-wide analysis of gene expression profile in the respiratory tree of sea cucumber (Apostichopus japonicus) in response to hypoxia conditions	Journal of the Marine Biological Association of the United Kingdom	1.038	2017	RNA-Seq
21	human	FH535 Inhibits Proliferation and Motility of Colon Cancer Cells by Targeting Wnt/β-catenin Signaling Pathway	Journal of Cancer	2.916	2017	RNA-Seq
22	Mouse	Data Descriptor: RNA sequencing analysis of activated macrophages treated with the anti-HIV ABX464 in intestinal inflammation	Scientific Data	4.836	2017	RNA-Seq
23	Mouse	Orally Administrated Baker’s Yeast beta-Glucan Promotes Glucose and Lipid Homeostasis in the Livers of ob/ob Mice	Journal of Agricultural and Food Chemistry	3.154	2017	RNA-Seq
24	Bradysia odoriphaga	Using Next-Generation Sequencing to Detect Differential Expression Genes in Bradysia odoriphaga after Exposure to Insecticides	International Journal of Molecular Sciences	3.226	2017	RNA-Seq
25	Antler cup coral	Systemic response of the stony coral Pocillopora damicornis against acute cadmium stress	Aquatic Toxicology	4.129	2017	RNA-Seq
26	Mouse	Characteristics of NK cells from leukemic microenvironment in MLL-AF9 induced acute myeloid leukemia	Molecular Immunology	3.236	2017	RNA-Seq
27	Sea cucumber	Differential gene expression in the intestine of sea cucumber (Apostichopus japonicus) under low and high salinity conditions	Comparative Biochemistry and Physiology D-Genomics & Proteomics	2.857	2017	RNA-Seq
28	Human cell line	Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblon‐independent manner	Molecular oncology	5.314	2017	RNA-seq
29	Human leukemia	Heterogeneous effects of M-CSF isoforms on the progression of MLL-AF9 leukemia	Immunology and cell biology	4.557	2017	RNA-seq
30	Ramie	Gene expression profiling of ramie roots during hydroponic induction and adaption to aquatic environment	Genomics Data	2.801	2017	RNA-Seq
31	human	Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells	Journal of Experimental & Clinical Cancer Research	5.189	2017	RNA-Seq
32	Penicillium	Identification of differentially expressed genes involved in spore germination of Penicillium expansum by comparative transcriptome and proteome approaches	MicrobiologyOpen	2.747	2017	RNA-Seq
33	Pancreatic ductal adenocarcinoma	High expression of diffuse panbronchiolitis critical region 1 gene promotes cell proliferation, migration and invasion in pancreatic ductal adenocarcinoma	Biochemical and Biophysical Research Communications	2.466	2017	RNA-Seq
34	human	Probing impaired neurogenesis in human brain organoids exposed to alcohol	Integrative Biology	3.252	2017	RNA-Seq
35	human	Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing	GigaScience	7.267	2017	metagenome
36	Salt grass	Transcriptome sequencing and comparative analysis of differentially-expressed isoforms in the roots of Halogeton glomeratus under salt stress	Gene	2.415	2017	RNA-Seq
37	Green carp	Transcriptomic analysis reveals transgenerational effect of hypoxia on the neural control of testicular functions	Aquatic Toxicology	4.129	2017	RNA-Seq
38	Mouse	Effects of In Utero PFOS Exposure on Transcriptome, Lipidome and Function of Mouse Testis	Environmental Science & Technology	6.198	2017	RNA-Seq
39	human	Germline and somatic variant identification using BGISEQ-500 and HiSeq X Ten whole genome sequencing	PLOS ONE	3.057	2018	WGS
40	Snail&oyster	Conserved and ubiquitous expression of piRNAs and PIWI genes in mollusks antedates the origin of somatic PIWI/piRNA expression to the root of bilaterians	bioRxiv		2018	Small RNA
41	Arabidopsis thaliana	Phytochrome A Negatively Regulates the Shade Avoidance Response by Increasing Auxin/Indole Acidic Acid Protein Stability	Developmental Cell	9.174	2018	RNA-Seq
42	watermelon	Comparative transcriptome analysis reveals key genes potentially related to soluble sugar and organic acid accumulation in watermelon	PLOS ONE	3.057	2018	RNA-Seq
43	Artemisia annua	A novel HD-ZIP IV/MIXTA complex promotes glandular trichome initiation and cuticle development in Artemisia annua	New Phytologist	7.33	2018	RNA-Seq
44	human	A novel mutation in PRPF31, causative of autosomal dominant retinitis pigmentosa, using the BGISEQ-500 sequencer	International journal of ophthalmology	1.1	2018	WES
45	Rat	Preinduction with bone morphogenetic protein-2 enhances cardiomyogenic differentiation of c-kit+ mesenchymal stem cells and repair of infarcted myocardium	International Journal of Cardiology	6.189	2018	RNA-seq
46	Arabidopsis thaliana	The GARP/MYB-related grape transcription factor AQUILO improves cold tolerance and promotes the accumulation of raffinose family oligosaccharides	Journal of Experimental Botany	5.83	2018	RNA-seq
47	human	An integrated biomanufacturing platform for the large-scale expansion and neuronal differentiation of human pluripotent stem cell-derived neural progenitor cells"	Acta Biomaterialia	6.319	2018	RNA-seq
48	Mouse	Cambogin suppresses dextran sulphate sodium‐induced colitis by enhancing Treg cell stability and function	British journal of pharmacology	5.49	2018	RNA-seq
49	Human cell line	FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathway	Cell death & disease	5.965	2018	RNA-seq
50	Arabidopsis thaliana	Arabidopsis thaliana ACS8 plays a crucial role in the early biosynthesis of ethylene elicited by Cu2+ ions	JOURNAL OF CELL SCIENCE	4.431	2018	RNA-seq
51	Mouse	Dual extra-retinal origins of microglia in the model of retinal microglia repopulation	Cell Discovery		2018	RNA-Seq
52	human	Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase	Theranostics	8.766	2018	RNA-Seq
53	Pea	A small set of differentially expressed genes was associated with two color morphs in natural populations of the pea aphid Acyrthosiphon pisum	Gene	2.415	2018	RNA-Seq
54	human	Selenite and methylseleninic acid epigenetically affects distinct gene sets in myeloid leukemia: A genome wide epigenetic analysis	Free Radical Biology and Medicine	5.606	2018	RNA-Seq
55	Mouse	Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion	Nature Neuroscience	17.839	2018	RNA-Seq
56	metagenome	A novel affordable reagent for room temperature storage and transport of fecal samples for metagenomic analyses	Microbiome	8.496	2018	metagenome
57	tomato	Transcriptome resequencing analysis of the responses of Ty5-Mediated resistance to TYLCV via in resistant vs. susceptible tomato cultivars	PeerJ	2.17	2018	RNA-seq
58	metagenome	Efficacy and safety of faecal microbiota transplantation in patients with psoriatic arthritis: protocol for a 6-month, double-blind, randomised, placebo-controlled trial	BMJ OPEN	2.369	2018	metagenome
59	Human cell line	Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival	Cell death & disease	5.965	2018	RNA-seq
60	Mouse	KRAB-type zinc-finger proteins PITA and PISA specifically regulate p53-dependent glycolysis and mitochondrial respiration	Cell research	15.606	2018	RNA-seq
61	Mouse	The LIS1/NDE1 Complex Is Essential for FGF Signaling by Regulating FGF Receptor Intracellular Trafficking	Cell Reports	8.282	2018	RNA-Seq
62	plant	A guide to sequence your favorite plant genomes	Applications in plant sciences	1.49	2018	Review
63	Human gastric cancer	The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1	Molecular Cancer	6.204	2018	RNA-seq
64	Rhizopus	Comparative genome-wide analysis of extracellular small RNAs from the mucormycosis pathogen Rhizopus delemar	Scientific Reports	4.259	2018	Small RNA
65	Thyroid cancer	TBX3 promotes proliferation of papillary thyroid carcinoma cells through facilitating PRC2-mediated p57KIP2 repression	Oncogene	7.519	2018	RNA-seq
66	Gastric cancer	Silkworm Pupa Protein Hydrolysate Induces Mitochondria-Dependent Apoptosis and S Phase Cell Cycle Arrest in Human Gastric Cancer SGC-7901 Cells	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	3.226	2018	RNA-seq
67	Arabidopsis thaliana	Hydrogen peroxide positively regulates brassinosteroid signaling through oxidation of the BRASSINAZOLE-RESISTANT1 transcription factor	Nature Communications	12.124	2018	RNA-seq
68	Human cell line	Small molecules capable of activating DNA methylation–repressed genes targeted by the p38 mitogen-activated protein kinase pathway	Journal of Biological Chemistry	4.125	2018	RNA-seq
69	Mouse	PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis	Developmental cell	9.174	2018	RNA-seq
70	leukemia	Leukemia cell-derived microvesicles induce T cell exhaustion via miRNA delivery	OncoImmunology	7.719	2018	RNA-seq
71	Saccharomyces cerevisiae	RNA-Seq analysis of global transcriptomic changes suggests a roles for the MAPK pathway and carbon metabolism in cell wall maintenance in a Saccharomyces cerevisiae FKS1 mutant	Biochemical and Biophysical Research Communications	2.466	2018	Transcriptome Sequencing
72	kava	The biosynthetic origin of psychoactive kavalactones in kava	bioRxiv		2018	Transcriptome Sequencing
73	Listeria	Identification and Characterization of als Genes Involved in D-Allose Metabolism in Lineage II Strain of Listeria monocytogenes	Frontiers in Microbiology	4.076	2018	RNA-seq
74	Cupriavidus	In Situ Lignin Bioconversion Promotes Complete Carbohydrate Conversion of Rice Straw by Cupriavidus basilensis B-8	ACS Sustainable Chemistry & Engineering	5.95	2018	RNA-seq
75	Rat	Cranial Irradiation Induces Hypothalamic Injury and Late-Onset Metabolic Disturbances in Juvenile Female Rats	DEVELOPMENTAL NEUROSCIENCE	3.03	2018	RNA-seq
76	human	Anti?fbrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn’s Disease	Digestive Diseases and Sciences	2.875	2018	RNA-seq
77	human	Quality Control of Next-generation Sequencing-based In vitro Diagnostic Test for Onco-relevant Mutations Using Multiplex Reference Materials in Plasma	Journal of Cancer	2.916	2018	Review
78	psoriasis	An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin Inflammation	Immunity	22.845	2018	RNA-seq
79	Human cell line	Roles of the CSE1L-mediated nuclear import pathway in epigenetic silencing	PNAS	9.661	2018	RNA-seq
80	Wheat rhizosphere	The Catabolite Repressor/Activator Cra Is a Bridge Connecting Carbon Metabolism and Host Colonization in the Plant Drought Resistance-Promoting Bacterium Pantoea alhagi LTYR-11Z	Applied and Environmental Microbiology	3.807	2018	RNA-seq
81	human	Efficient and unique co-barcoding of second-generation sequencing reads from long DNA molecules enabling cost effective and accurate sequencing, haplotyping, and de novo assembly	GENOME RESEARCH	11.922	2019	stLFR
82	Corn worm	Transcriptome profiling reveals differential gene expression of detoxification enzymes in Sitophilus zeamais responding to terpinen-4-ol fumigation	Pesticide Biochemistry and Physiology	2.59	2018	Transcriptome Sequencing
83	human	Identification of a mutL?homolog 1 mutation via whole?exome sequencing in a Chinese family with Gardner syndrome	Molecular Medicine Reports	1.692	2018	WES
84	E.coli	Differential gene expression in Escherichia coli during aerosolization from liquid suspension	Applied Microbiology and Biotechnology	3.42	2018	RNA-seq
85	Rat intestine	A gene catalogue of the Sprague-Dawley rat gut metagenome	GigaScience	7.267	2018	metagenome
86	Dracaena cambodiana	Complete plastome sequence of Dracaena cambodiana (Asparagaceae): a species considered “Vulnerable” in Southeast Asia	Mitochondrial DNA Part B	0.488	2018	plastome Sequencing
87	Human exosomes	Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy	The American Journal of Human Genetics	9.025	2018	RNA-seq
88	Oyster	The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensis	Frontiers in Physiology	4.134	2018	RNA-seq
89	Arabidopsis thaliana	Overexpression of VaWRKY14 increases drought tolerance in Arabidopsis by modulating the expression of stress-related genes	Plant Cell Reports	2.869	2018	RNA-seq
90	Salt mustard	Compositional and transcriptomic analysis associated with cuticle lipid production on rosette and inflorescence stem leaves in the extremophyte Thellungiella salsuginea	physiologia plantarum	3.3	2018	RNA-seq
91	yeast	Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods	Nature Communications	12.124	2018	WGS
92	Mouse	Global expression profiling and pathway analysis of mouse mammary tumor reveals strain and stage specific dysregulated pathways in breast cancer progression	Cell Cycle	3.53	2018	RNA-seq
93	human	STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection	Nature Communications	12.124	2018	RNA-seq
94	Rice	DDM1 represses noncoding RNA expression and RNA-directed DNA methylation in heterochromatin	Plant Physiology	6.456	2018	Small RNA
95	Rhesus monkey	Genetic screening and multipotency in rhesus monkey haploid neural progenitor cells	Development	5.843	2018	RNA-seq
96	Human cleft lip	A novel PTCH1 mutation underlies non‐syndromic cleft lip and/or palate in a Han Chinese family	oral diseases	2.01	2018	WES
97	Sogatella furcifera	Comparative transcriptome analysis of Sogatella furcifera (Horváth) exposed to different insecticides	Scientific Reports	4.259	2018	Transcriptome Sequencing
98	Infective endocarditis	Identification of pathogens in culture-negative infective endocarditis with metagenomic analysis	Annals of Clinical Microbiology and Antimicrobials	3.155	2018	metagenome
99	human	Reliable Multiplex Sequencing with Rare Index Mis-Assignment on DNB-Based NGS Platform	BMC Genomics	3.73	2018	WGS&PCR-Free
100	Human cell line	Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy	Journal of Pharmacology and Experimental Therapeutics	3.867	2018	RNA-seq&Small RNA
101	Cynoglossus semilaevis	Transcriptome profiling of immune-responsive genes in the intestine of Cynoglossus semilaevis Günther challenged with Shewanella algae	Fish & Shellfish Immunology	3.148	2018	RNA-seq
102	tomato	Expression of grape ACS1 in tomato decreases ethylene and alters the balance between auxin and ethylene during shoot and root formation	Journal of Plant Physiology	3.121	2018	RNA-seq
103	Ovarian cancer	C/EBPβ enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation	Nature Communications	12.124	2018	WES
104	Mycobacterium	Diagnosis of local hepatic tuberculosis through next-generation sequencing: Smarter, faster and better	Clinics and Research in Hepatology and Gastroenterology	2.623	2018	Pathogen detection
105	cucumber	Differential Gene Expression Caused by the F and M Loci Provides Insight Into Ethylene-Mediated Female Flower Differentiation in Cucumber	Front. Plant Sci.	3.678	2018	RNA-seq
106	Spontaneous preterm birth	Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth	PLOS.Genetics	5.54	2018	WES
107	Parasitic wasp	Parasitic insect-derived miRNAs modulate host development	Nature Communications	12.124	2018	Small RNA
108	human	The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer.	J Pathol	6.253	2018	RNA-seq
109	Human cell line	Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth	Nature Communications	12.124	2018	RNA-Seq
110	Human interstitial cells	Differential and Interactive Effects of Substrate Topography and Chemistry on Human Mesenchymal Stem Cell Gene Expression	International Journal of Molecular Sciences.	3.687	2018	RNA-Seq
111	Arabidopsis thaliana	Comparative performance of the BGISEQ-500 and Illumina HiSeq4000 sequencing platforms for transcriptome analysis in plants	Plant Methods	4.269	2018	RNA-seq
112	Rice	Modulating plant growth–metabolism coordination for sustainable agriculture	Nature	41.577	2018	RNA-Seq&ChIP-Seq
113	Mouse	Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation	Neuron	14.318	2018	RNA-Seq
114	human	3 Branch ligation: a novel method to ligate non-complementary DNA to recessed or internal 30OH ends in DNA or RNA	DNA RES	5.404	2018	stLFR
115	human	Validation of combinatorial probe–anchor ligation-based sequencing as non-invasive prenatal test for trisomy at a central laboratory	Ultrasound in Obstetrics & Gynecology	4.71	2017	NIFTY
116	plant	10KP: A Phylodiverse Genome Sequencing Plan	GigaScience	7.267	2018	COMMENTARY
117	fish	Chromosome-level reference genome of the Siamese fighting fish Betta splendens, a model species for the study of aggression	GigaScience	7.267	2018	Hi-C library
118	tomato	Comparative Transcriptome Profiling of Two Tomato Genotypes in Response to Potassium-Deficiency Stress	International Journal of Molecular Sciences	3.687	2018	RNA-Seq
119	human	The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function	PLOS ONE	3.057	2018	Small RNA
120	human	The metagenome of the female upper reproductive tract	GigaScience	7.267	2018	metagenome
121	virus	clinical application of respiratory virus detection by metagenomic next generation sequencing	Chinese Journal of Nosocomiology(china)		2018	metagenome
122	Alfalfa	Multiple Regulatory Networks Are Activated during Cold Stress in Medicago sativa L	International Journal of Molecular Sciences	3.687	2018	RNA-Seq
123	Rat	Hippocampal gene expression profiling in a rat model of functional constipation reveals abnormal expression genes associated with cognitive function	Neuroscience Letters	2.18	2018	RNA-Seq
124	human	Advanced Whole-Genome Sequencing and Analysis of Fetal Genomes from Amniotic Fluid	Clinical Chemistry	8.636	2018	PGS
125	human	Isolation and whole genome sequencing of fetal cells from maternal blood towards the ultimate non‐invasive prenatal testing	PRENATAL DIAGNOSIS	2.523	2017	PGS
126	human	Multiplex Cell-Free DNA Reference Materials for Quality Control of Next-Generation Sequencing-Based In Vitro Diagnostic Tests of Colorectal Cancer Tolerance	Journal of Cancer	2.916	2018	cfDNA
127	Mouse	Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis	Annals of the Rheumatic Diseases	12.38	2018	RNA-Seq
128	Human cell line	The epigenetic modifer PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer	Journal of Pathology	6.253	2018	RNA-Seq
129	Mouse	Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice	Carbohydrate Polymers	5.158	2018	RNA-Seq
130	Zebrafish	Transcriptome analysis reveals functional roles of nacreous protein N16 in prednisolone-induced osteoporotic zebrafish	International Journal of Biological Macromolecules	3.909	2018	RNA-Seq
131	peanut	Comparative transcriptome analysis revealed key factors for differential cadmium transport and retention in roots of two contrasting peanut cultivars	BMC genomics	3.73	2018	RNA-Seq
132	Alfalfa	Comparative Transcriptomic and Physiological Analyses of Medicago sativa L. Indicates that Multiple Regulatory Networks Are Activated during Continuous ABA Treatment	Int J Mol Sci.	3.687	2018	RNA-Seq
133	Oyster	Analysis of in situ Transcriptomes Reveals Divergent Adaptive Response to Hyper- and Hypo-Salinity in the Hong Kong Oyster, Crassostrea hongkongensis	Front. Physiol	3.394	2018	RNA-Seq
134	Heortia vitessoides	Candidate olfactory genes identified in Heortia vitessoides(Lepidoptera: Crambidae) by antennal transcriptome analysis	Comparative Biochemistry and Physiology Part D: Genomics and Proteomics	2.913	2018	Transcriptome Sequencing
135	barley	Transcriptomic comparison of two barley genotypes differing in arsenic tolerance exposed to arsenate and phosphate treatments	Plant Physiology and Biochemistry	2.718	2018	RNA-Seq
136	alveolar macrophages	Transcriptome of porcine alveolar macrophages activated by interferon-gamma and lipopolysaccharide	Biochemical and Biophysical Research Communications	2.559	2018	RNA-Seq
137	Salt grass	Comparative transcriptome analysis of genes involved in Na+ transport in the leaves of halophyte Halogeton glomeratus	Gene	2.498	2018	RNA-seq
138	duck	RNA-Seq analysis of duck embryo fibroblast cell gene expression during the early stage of egg drop syndrome virus infection	Poultry Science	2.216	2018	RNA-Seq
139	Heortia vitessoides	De novo assembly and identification of antennal transcriptome reveals an olfactory system in Heortia vitessoides (Lepidoptera: Crambidae)	PeerJ	2.17	2017	Transcriptome Sequencing
140	Jujube	Combination of iTRAQ proteomics and RNA-seq transcriptomics reveals jasmonate-related-metabolisms central regulation during the process of Jujube witches’ broom recovery by tetracycline treatment	Scientia Horticulturae	1.76	2018	RNA-seq
141	human	The application of NIPT using combinatorial probe-anchor synthesis to identify sex chromosomal aneuploidies (SCAs) in a cohort of 570 pregnancies.	Mol Cytogenet.	1.167	2018	NIFTY
142	Cell line	A new massively parallel nanoball sequencing platform for whole exome research	BMC Bioinformatics	2.448	2019	WES
143	Mouse embryo Stem cells&human K562 cells	Comparative analysis of sequencing technologies platforms for single-cell transcriptomics	GENOME BIOLOGY	13.214	2019	scRNA-Seq
144	Purple cabbage, kale	Maintenance of grafting-induced epigenetic variations in the asexual progeny of Brassica oleracea and B juncea chimera	Plant J	5.97	2018	Small RNA
145	Exosomes	Exosomes derived from preadipocytes improve osteogenic differentiation, potentially via reduced miR?223 expression	Molecular Medicine Reports	1.692	2018	RNA-Seq
146	Caenorhabditis elegans	A Persistence Detector for Metabolic Network Rewiring in an Animal	CELL REP	8.282	2019	RNA-Seq
147	human	An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos	Nature Communications	12.124	2019	ATAC-seq&LiCAT-seq
148	Gram-positive bacteria	Functional analysis of Leifsonia xyli subsp xyli membrane protein gene Lxx18460 (anti-sigma K)	BMC Microbiol	2.644	2019	RNA-Seq
149	Celastrus angulatus maxim	De novo leaf and root transcriptome analysis to explore biosynthetic pathway of Celangulin V in Celastrus angulatus maxim	BMC GENOMICS	3.729	2019	RNA-Seq
150	human	Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity	Nature Communications	12.124	2019	scCAT-seq
151	Nematode	The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans	PLOS GENET	6.1	2019	RNA-Seq&ChIP-seq
152	Mouse	Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue	PLOS BIOL	9.797	2019	RNA-Seq
153	Rice	The basic helix‐loop‐helix transcription factor, OsPIL15, regulates grain size via directly targeting a purine permease gene OsPUP7 in rice	PLANT BIOTECHNOL J	7.443	2019	RNA-Seq
154	Brassica	Chromosome level comparative analysis of Brassica genomes	PLANT MOL BIOL	3.356	2019	Hi-C library
155	human	CINP is a novel cofactor of KLF5 required for its role in the promotion of cell proliferation, survival and tumor growth	INT J CANCER	6.513	2019	RNA-Seq
156	human	Knockdown of KDM2A inhibits proliferation associated with TGF-β expression in HEK293T cell	MOL CELL BIOL	4.398	2019	RNA-Seq
157	human	Toxoplasma gondii ROP17 inhibits the innate immune response of HEK293T cells to promote its survival	PARASITOL RES	2.329	2019	RNA-Seq
158	tomato	Overexpression of the KNOX gene Tkn4 affects pollen development and confers sensitivity to gibberellin and auxin in tomato	J PLANT BIOL	1.437	2019	RNA-Seq
159	tomato	A tomato B‐box protein SlBBX20 modulates carotenoid biosynthesis by directly activating PHYTOENE SYNTHASE 1, and is targeted for 26S proteasome‐mediated degradation	New Phytologist	7.33	2019	RNA-Seq
160	human	Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individuals	bioRxiv		2019	capture
161	Rice	Expression of Maize MADS Transcription Factor ZmES22 Negatively Modulates Starch Accumulation in Rice Endosperm	INT J MOL SCI	3.226	2019	RNA-Seq
162	human	MicroRNA profiling from dried blood samples	Critical Reviews in Clinical Laboratory Sciences	6.481	2019	Small RNA
163	Arabidopsis thaliana	Functional analysis for domains of maize PPR protein EMP5 in RNA editing and plant development in Arabidopsis	PLANT GROWTH REGUL	2.646	2019	RNA-Seq
164	human	Human epidermal growth factor receptor 2 amplification as a biomarker for treatment in patients with lymph node?metastatic penoscrotal extramammary Paget's disease	Oncology Letters	1.664	2019	WGS
165	Grouper	A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth	Molecular Ecology Resources	7.059	2019	RNA-Seq&ATAC-seq
166	Amphioxus	Genome-wide transcriptional response of microRNAs to the benzo(a)pyrene stresD168:D178s in amphioxus Branchiostoma belcheri	CHEMOSPHERE	4.208	2019	Small RNA
167	Zebrafish	Microcystin-LR exposure induced nephrotoxicity by triggering apoptosis in female zebrafish	CHEMOSPHERE	4.208	2019	RNA-Seq
168	human	Genomic sequencing and editing revealed the GRM8 signaling pathway as potential therapeutic targets of squamous cell lung cancer	CANCER LETT	6.375	2019	WGS&WES
169	human	Nonobese subjects of Bacteroides and Prevotella enterotypes responded differentially to calorie restriction intervention	bioRxiv		2019	metagenome
170	Alfalfa	Full-length transcript sequencing and comparative transcriptomic analysis to evaluate the contribution of osmotic and ionic stress components towards salinity tolerance in the roots of cultivated alfalfa (Medicago sativa L)	BMC Plant Biology	3.964	2019	RNA-Seq
171	human	Genome-wide identification of protein binding sites on RNAs in mammalian cells	Biochemical and Biophysical Research Communications	2.466	2019	RPBS-Cap
172	Amphioxus	Genome-wide gene expression analysis reveals novel insights into the response to nitrite stress in gills of Branchiostoma belcheri	CHEMOSPHERE	4.208	2019	RNA-Seq
173	Mouse	Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation	INT J CANCER	6.513	2018	RNA-Seq
174	Pathogen	Pathogens in Patients with Granulomatous lobular mastitis	INT J INFECT DIS	2.532	2019	Pathogen detection
175	human	The identification of a transthyretin variant p.D38G in a Chinese family with early-onset leptomeningeal amyloidosis	Journal of Neurology	3.783	2019	WES
176	bacterial	MALDI-TOF Characterization of Protein Expression Mutation During Morphological Changes of Bacteria Under the Impact of Antibiotics	ANAL CHEM	6.32	2019	RNA-Seq
177	Herpes Simplex Viruses	Identification of Putative UL54 (ICP27) Transcription Regulatory Sequences Binding to Oct-1, v-Myb, Pax-6 and Hairy in Herpes Simplex Viruses	Journal of Cancer	2.916	2019	Pathogen detection
178	Tropical fruit of Indonesia	Datasets for genome assembly of six underutilized Indonesian fruits	Data in Brief		2019	WGS
179	Brassica	The complete plastid genomes of four species from Brassicales	MITOCHONDR DNA part B	0.488	2019	plastome Sequencing
180	insect	Candidate olfactory genes identified in Heortia vitessoides (Lepidoptera: Crambidae) by antennal transcriptome analysis	Comparative Biochemistry and Physiology Part D: Genomics and Proteomics	2.857	2019	RNA-seq
181	virus	Genome comparison of African swine fever virus China/2018/AnhuiXCGQ strain and related European p72 Genotype II strains	TRANSBOUND EMERG DIS	3.585	2019	Pathogen detection
182	Sea worm family	Complete mitogenome of a Baltic Sea specimen of the non-indigenous polychaete Marenzelleria neglecta	MITOCHONDR DNA part B	0.488	2019	WGS
183	metagenome	Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report	journal of Bone and Joint Infection		2019	Pathogen detection
184	White whale	The first chromosome‐level genome for a marine mammal as a resource to study ecology and evolution	Molecular Ecology Resources	7.332	2019	WGS
185	metagenome	The vagino-cervical microbiome as a woman's life history	bioRxiv		2019	metagenome
186	Danionella translucida	Hybrid genome assembly and annotation of Danionella translucida	bioRxiv		2019	Transcriptome Sequencing
187	corn	Molecular Mechanisms Underlying Increase in Lysine Content of Waxy Maize through the Introgression of the opaque2 Allele	INT J MOL SCI	3.226	2019	RNA-Seq
188	penguin	Mitogenomes uncover extinct penguin taxa and reveal island formation as a key driver of speciation	Molecular Biology and Evolution	6.202	2019	WGS
189	metagenome	The biodiversity Composition of Microbiome in Ovarian Carcinoma Patients	Scientific Reports	4.259	2019	RNA-Seq
190	apple	Methylome and transcriptome analyses of apple fruit somatic mutations reveal the difference of red phenotype	BMC genomics	3.73	2019	RNA-Seq
191	tomato	SlMYB75, an MYB-type transcription factor,promotes anthocyanin accumulation and enhances volatile aroma production in tomato fruits	Horticulture Research	3.6	2019	RNA-Seq
192	Mouse	The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice	Toxicology	3.582	2019	RNA-Seq
193		Molecular digitization of a botanical garden: high-depth whole genome sequencing of 689 vascular plant species from the Ruili Botanical Garden	GigaScience	7.267	2019	WGS
194	American ginseng	Characterization of the complete chloroplast genome of American ginseng, Panax quinquefolius L.	Mitochondrial DNA Part B	0.488	2019	chloroplast Sequencing
195	Nanmu	Characterization of the complete chloroplast genome of the Phoebe zhennan S. Lee	Mitochondrial DNA Part B	0.488	2019	chloroplast Sequencing
196	eggplant	Comparative transcriptome analysis reveals K+ transporter gene contributing to salt tolerance in eggplant	BMC Plant Biology	3.964	2019	RNA-Seq
197	Mouse	Eradication of glioblastoma by immuno-virotherapy with a retargeted oncolytic HSV in a preclinical model	Oncogene	7.519	2019	RNA-Seq
198	Bradysia odoriphaga	Genome-wide analysis of developmental stage-specific transcriptome in Bradysia odoriphaga	Comparative Biochemistry and Physiology D-Genomics & Proteomics	2.857	2019	RNA-Seq
199	human	A Novel Heterozygous Mutation of the COL4A3 Gene Causes a Peculiar Phenotype without Hematuria and Renal Function Impairment in a Chinese Family	DISEASE MARKERS	2.348	2019	WES
200	human	Comparative performance of the BGI and Illumina sequencing technology for single-cell RNA sequencing	bioRxiv		2019	scRNA-Seq
201	Rat	Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro	Aging	5.179	2019	RNA-Seq
202	Lactobacillus	Two Strains of Lactobacilli Effectively Decrease the Colonization of VRE in a Mouse Model	Frontiers in cellular and Infection Microbiology	3.52	2019	RNA-Seq
203	dog	Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival	bioRxiv		2019	RNA-Seq
204	human	Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells	Nucleic Acids Research	10.162	2019	RNA-Seq
205	human	Specific Decrease in B-Cell-Derived Extracellular Vesicles Enhances Post-Chemotherapeutic CD8+ T Cell Responses	Immunity	22.845	2019	RNA-Seq
206	Mouse	Ex Vivo Hepatocyte Reprograming Promotes Homology‐Directed DNA Repair to Correct Metabolic Disease in Mice After Transplantation	hepatology communications		2019	RNA-Seq
207	Rodents	Hepatic IRF6 alleviates liver steatosis and metabolic disorder by transcriptionally suppressing PPARγ	hepatology	13.246	2019	RNA-Seq&ChIP-Seq
208	Neisseria gonorrhoeae	Identification and expression analysis of ceftriaxone resistance-related genes in Neisseria gonorrhoeae integrating RNA-Seq data and qRT-PCR validation	Journal of Global Antimicrobial Resistance	1.276	2019	RNA-Seq
209	human	Identification of a Heterozygous Mutation in the TGFBI Gene in a Hui-Chinese Family with Corneal Dystrophy	Journal of Ophthalmology	1.712	2019	RNA-Seq
210	Rice	OsHLH61-OsbHLH96 influences rice defense to brown planthopper through regulating the pathogen-related genes	rice	3.739	2019	RNA-Seq
211	Arabidopsis thaliana	The R2R3-MYB transcription factor MYB49 regulates cadmium accumulation	Plant physiology	6.456	2019	RNA-Seq
212	oilseed rape	Transcriptome analysis of the irregular shape of shoot apical meristem in dt (dou tou) mutant of Brassica napus L.	Molecular Breeding	2.465	2019	RNA-Seq
213	potato	Sequencing and characterization the complete chloroplast genome of the potato, Solanum tuberosum L.	MITOCHONDR DNA part B	0.488	2019	chloroplast Sequencing
214	human	Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome	Nature Communications	12.124	2019	RNA-Seq
215	Mouse	Transcriptome Profile in Hippocampus During Acute Inflammatory Response to Surgery: Toward Early Stage of PND	Frontiers in Immunology	6.429	2019	RNA-Seq
216	Dandelion	Dandelion polysaccharides exert anticancer effect on Hepatocellular carcinoma by inhibiting PI3K/AKT/mTOR pathway and enhancing immune response	Journal of Functional Foods	3.144	2019	RNA-Seq
217	peach	A single nucleotide mutation in GID1c disrupts its interaction with DELLA1 and causes a GA‐insensitive dwarf phenotype in peach	PLANT BIOTECHNOLOGY JOURNAL	7.443	2019	RNA-Seq
218	Nude mouse	RREB1-induced upregulation of the lncRNA AGAP2-AS1 regulates the proliferation and migration of pancreatic cancer partly through suppressing ANKRD1 and ANGPTL4	Cell Death & Disease	5.965	2019	RNA-Seq
219	human	CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis	Immunity	22.845	2019	RNA-Seq
220	Mouse	Intestinal transcriptional profling reveals fava bean-induced immune response in DBA/1 mice	Biological Research	1.692	2019	RNA-Seq
221	Anabas testudineus	Transcriptomic analysis of Anabas testudineus and its defensive mechanisms in response to persistent organic pollutants exposure	SCIENCE OF THE TOTAL ENVIRONMENT	4.9	2019	RNA-Seq
222	Yak	Nutritional Interventions Improved Rumen Functions and Promoted Compensatory Growth of Growth-Retarded Yaks as Revealed by Integrated Transcripts and Microbiome Analyses	Frontiers in microbiology	4.076	2019	RNA-Seq
223	human	The proinflammatory cytokine TNF-α induces DNA demethylation–dependent and –independent activation of interleukin-32 expression	Journal of Biological Chemistry	4.125	2019	RNA-Seq
224	Diatom	Complete chloroplast genome of the diatom Skeletonema pseudocostatum from the Western Mediterranean coast of Algeria	MITOCHONDR DNA part B	0.488	2019	chloroplast Sequencing
225	human	COL1A2 p.Gly1066Val variant identified in a Han Chinese family with osteogenesis imperfecta type I	molecular genetics&genomics	2.979	2019	WES
226	human	Establishment of a human embryonic stem cell-based liver differentiation model for hepatotoxicity evaluations	Ecotoxicology and Environmental Safety	3.743	2019	RNA-Seq
227	mouse	Germline deletion of Cdyl causes teratozoospermia and progressive infertility in male mice	Cell Death & Disease	5.965	2019	RNA-seq
228	human	Novel GLI3 mutations in Chinese patients with non-syndromic post-axial polydactyly	CURRENT MOLECULAR MEDICINE	2.345	2019	WES
229	Horseshoe	RNA-Seq analysis of gene expression during the yellowing developmental process of fresh-cut Chinese water chestnuts	Scientia Horticulturae	1.624	2019	RNA-seq
230	fish	Hypoxia causes transgenerational impairment of ovarian development and hatching success in fish	ENVIRONMENTAL SCIENCE & TECHNOLOGY	6.198	2019	RNA-seq
231	human	Integrated lipidomics and transcriptomics characterization upon aging related changes of lipid species and pathways in human bone marrow mesenchymal stem cells	JOURNAL OF PROTEOME RESEARCH	4.268	2019	RNA-seq
232	mouse	Toxicity Induced by Zirconia Oxide Nanoparticles on Various Organs After Intravenous Administration in Rats	Journal of Biomedical Nanotechnology	4.521	2019	RNA-seq
233	human	Comparative analysis of novel MGISEQ-2000 sequencing platform vs Illumina HiSeq 2500 for whole-genome sequencing	bioRxiv		2019	WGS
234	human	Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination	Neuron	14.318	2019	RNA-seq
235	human	Generation of Highly Biomimetic Quality Control Materials for Noninvasive Prenatal Testing Based on Enzymatic Digestion of Matched Mother–Child Cell Lines	CLINICAL CHEMISTRY	8.008	2019	NIFTY
236	Salvia	Comparative transcriptomic analysis provides insights into the development of a Salvia splendens Ker-Gawler mutant, SX919M	PLoS One	2.806	2019	RNA-seq
237	mouse	Absence of GdX/UBL4A Protects against Inflammatory Diseases by Regulating NF-кB Signaling in Macrophages and Dendritic Cells	Theranostics	8.712	2019	RNA-seq
238	mouse	Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT	Molecular Cancer	6.204	2019	RNA-seq
239	Microalgae	Transcriptomic and lipidomic analysis of an EPA-containing Nannochloropsis sp. PJ12 in response to nitrogen deprivation	Scientific Reports	4.259	2019	RNA-seq
240	human	Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN	Theranostics	8.712	2019	RNA-seq
241	Arabidopsis thaliana	Comparative physiological and transcriptomic analyses reveal the toxic effects of ZnO nanoparticles on plant growth	ENVIRONMENTAL SCIENCE & TECHNOLOGY	6.198	2019	RNA-seq
242	Spider Mite	Identification of Saliva Proteins of the Spider Mite Tetranychus evansi by Transcriptome and LC–MS/MS Analyses	PROTEOMICS	4.041	2018	RNA-seq
243	Mosquito	Mosquito Small RNA Responses to West Nile and Insect-Specific Virus Infections in Aedes and Culex Mosquito Cells	viruses	3.761	2019	Small RNA
244	Rose yellow mosaic virus	Complete genome sequence of a novel member of the family Potyviridae isolated from Phellodendron amurense Rupr. in Liaoning, China	ARCHIVES OF VIROLOGY	2.058	2019	Small RNA
245	mouse	An ATAC-seq atlas of chromatin accessibility in mouse tissues	Scientific Data	5.305	2019	ATAC-seq
246	metagenome	Life history recorded in the vagino-cervical microbiome	bioRxiv		2019	metagenome
247	human	MicroRNA signature of air pollution exposure‐induced congenital defects	JOURNAL OF CELLULAR PHYSIOLOGY	4.08	2019	Small RNA
248	human	Decitabine shows synergistic effects with arsenic trioxide against myelodysplastic syndrome cells via endoplasmic reticulum stress-related apoptosis	Journal of Investigative Medicine	1.943	2019	RNA-seq
249	human	Panel-based NGS reveals disease-causing mutations in hearing loss patients using BGISEQ-500 platform	MEDICINE	1.803	2019	capture
250	human	Super-enhancers: novel target for pancreatic ductal adenocarcinoma	oncotarget	5.168	2019	RNA-Seq&ChIP-Seq
251	bacterial	An Osmoregulatory Mechanism Operating through OmpR and LrhA Controls the Motile-Sessile Switch in the Plant Growth-Promoting Bacterium Pantoea alhagi	APPLIED AND ENVIRONMENTAL MICROBIOLOGY	3.807	2019	RNA-Seq
252	mouse	Metabolic Profiling of Tumors, Sera, and Skeletal Muscles from an Orthotopic Murine Model of Gastric Cancer Associated-Cachexia	JOURNAL OF PROTEOME RESEARCH	4.268	2019	RNA-Seq
253	Human cell line	Targeting super-enhancer-driven oncogenic transcription by CDK7 inhibition in anaplastic thyroid cancer	THYROID	5.515	2019	RNA-Seq&ChIP-Seq
254	Caenorhabditis elegans	Gene-level quantitative trait mapping in an expanded C. elegans multiparent experimental evolution panel	bioRxiv		2019	WGS
255	tomato	Characterization the complete chloroplast genome of the tomato (Solanum lycopersicum L.) from China	MITOCHONDR DNA part B	0.488	2019	chloroplast Sequencing
256	Pathogen	High‐throughput identification and diagnostics of pathogens and pests: Overview and practical recommendations	Molecular Ecology Resources	7.332	2018	Pathogen detection
257	porcine sapelovirus	Characterization and epidemiological survey of porcine sapelovirus in China	Veterinary Microbiology	2.628	2019	Pathogen detection
258	Salmonella enteritidis	Increased growth rate and amikacin resistance of Salmonella enteritidis after one‐month spaceflight on China’s Shenzhou‐11 spacecraft	Microbiologyopen	2.747	2019	Pathogen detection
259	Fungus	Intercellular communication is required for trap formation in the nematode-trapping fungus Duddingtonia flagrans	PLOS.Genetics	5.54	2019	RNA-Seq
260	Human cell line	Next-Generation Sequencing Analysis of mRNA Profile in Cisplatin-Resistant Gastric Cancer Cell Line SGC7901	Med Sci Monit	1.585	2019	RNA-Seq
261	Verticillium dahliae	Genomewide Transcriptome Profiles Reveal How Bacillus subtilis Lipopeptides Inhibit Microsclerotia Formation in Verticillium dahliae	MOLECULAR PLANT-MICROBE INTERACTIONS	4.332	2019	RNA-Seq
262	Human cell line	Human UTP14a promotes angiogenesis through upregulating PDGFA expression in colorectal cancer	BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS	2.466	2019	RNA-Seq
263	Chlorella	The Complete Chloroplast Genome of Tetraselmis desikacharyi (Chlorodendrophyceae) and Phylogenetic Analysis	Mitochondrial DNA Part B	0.48	2019	chloroplast Sequencing
264	Flatworm	Complete mitogenome of the giant invasive hammerhead flatworm Bipalium kewense	MITOCHONDR DNA part B	0.488	2019	MtDNA sequencing
265	virus	The complete nucleotide sequence and genome organization of a novel virus of the order Tymovirales isolated from Prunus davidiana (Carr.) Franch. in Liaoning, China	Archives of Virology	2.058	2019	Small RNA
266	Monascus	A Comprehensive Analysis of the Small GTPases Ypt7 Involved in the Regulation of Fungal Development and Secondary Metabolism in Monascus ruber M7	Frontiers in Microbiology	4.076	2019	RNA-Seq
267	corn	Maize VIVIPAROUS1 Interacts with ABA INSENSITIVE5 to Regulate GALACTINOL SYNTHASE2 Expression Controlling Seed Raffinose Accumulation	Journal of Agricultural and Food Chemistry	3.154	2019	RNA-Seq
268	Human cell line	Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection	International Journal of Molecular Sciences	3.226	2019	Small RNA
269	Human cell line	MicroRNA profiling of plasma exosomes from patients with ovarian cancer using high?throughput sequencing	Oncology Letters	1.664	2019	Small RNA
270	Zebrafish	Acute exposure to ustiloxin A affects growth and development of early life zebrafish, Danio rerio	Chemosphere	4.208	2019	RNA-Seq
271	Mouse	Identification of key genes, pathways, and miRNA/mRNA regulatory networks of CUMS-induced depression in nucleus accumbens by integrated bioinformatics analysis	Neuropsychiatric Disease and Treatment	2.198	2019	RNA-seq&Small RNA
272	metagenome	A multi-omic cohort as a reference point for promoting a healthy human gut microbiome	bioRxiv		2019	metagenome
273	human	Identifying a BRCA2 c.5722_5723del mutation in a Han-Chinese family with breast cancer	BIOSCIENCE REPORTS	2.906	2019	WES
274	Sorghum	Characterization of the complete chloroplast genome of the Chinese sorghum, Sorghum bicolor from China	MITOCHONDR DNA part B	0.488	2019	chloroplast Sequencing
275	Whale	The Marine Mammal Class II Major Histocompatibility Complex Organization	Frontiers in Immunology	6.429	2019	WGS
276	grass carp	Transcriptome analysis of rare minnow (Gobiocypris rarus) infected by the grass carp reovirus	Fish & Shellfish Immunology	3.185	2019	RNA-Seq
277	Human cell line	Irradiation-induced dynamic changes of gene signatures reveal gain of metastatic ability in nasopharyngeal carcinoma	American Journal of Cancer Research	3.998	2019	RNA-Seq
278	Cartilage fish	Dynamic chromosome rearrangements of the white-spotted bamboo shark shed light on cartilaginous fish diversification mechanisms	bioRxiv		2019	WGS&Hi-C library&RNA-Seq
279	human	Novel DPY19L2 variants in globozoospermic patients and the overcoming this male infertility	ASIAN JOURNAL OF ANDROLOGY	3.259	2019	WES
280	Mouse	Pharmacological and transcriptome profiling analyses of Fufang E'jiao Jiang during chemotherapy-induced myelosuppression in mice	Journal of Ethnopharmacology	3.115	2019	RNA-Seq
281	human	Whole genome sequencing reveals complexity in both HPV sequences present and HPV integrations in HPV-positive oropharyngeal squamous cell carcinomas	BMC Cancer	3.288	2019	WGS
282	Cattle	Genomic variants identified from whole-genome resequencing of indicine cattle breeds from Pakistan	Plos one	2.766	2019	WGS
283	frog	Integrated mRNA and miRNA expression profile analyses reveal the potential roles of sex‐biased miRNA–mRNA pairs in gonad tissues of the Chinese concave‐eared torrent frog (Odorrana tormota)	JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION	2.432	2019	RNA-seq&Small RNA
284	Arabidopsis thaliana	The H3K27me3 demethylase REF6 promotes leaf senescence through directly activating major senescence regulatory and functional genes in Arabidopsis	PLOS.Genetics	5.54	2019	RNA-Seq
285	Collembola	Developmental Expression and Evolution of Hexamerin and Hemocyanin from Folsomia candida (Collembola)	INSECT MOLECULAR BIOLOGY	2.492	2019	RNA-Seq
286	Mouse	Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism	Cell Reports	8.282	2019	RNA-Seq
287	human	Frizzled 2‐induced epithelial‐mesenchymal transition correlates with vasculogenic mimicry, stemness, and Hippo signaling in hepatocellular carcinoma	cancer science	4.372	2019	RNA-Seq
288	Streptococcus thermophilus	Study on high throughput sequencing genomic DNA extraction of streptococcus scarlet fever	South China Journal Of Preventive Medicine(china)		2019	Pathogen detection
289	broad bean	Identification and Characterization of Salt-Responsive MicroRNAs in Vicia faba by High-Throughput Sequencing	genes	3.191	2019	Small RNA
290	Human cell line	Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer	Molecular Cancer	7.776	2019	ChIP-seq
291	human	Single cell RNA sequencing reveals cellular diversity of trisomy 21 retina	bioRxiv		2019	scRNA-Seq
292	human	Single cell RNA-seq reveals cellular diversity and developmental characteristics of human infant retina	bioRxiv		2019	scRNA-Seq
293	corn	Transcriptome Dynamics of Double Recessive Mutant, o2o2o16o16, Reveals the Transcriptional Mechanisms in the Increase of Its Lysine and Tryptophan Content in Maize	genes	3.191	2019	RNA-Seq
294	Human cell line	LFMD: a new likelihood-based method to detect low-frequency mutations without molecular tags	bioRxiv		2019	MtDNA sequencing
295	Mouse	YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis	Cell Reports	8.282	2019	RNA-Seq
296	Mouse	Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate	CELL RESEARCH	15.393	2019	RNA-Seq
297	Zebrafish	Primary cilia regulate hematopoietic stem and progenitor cell specification through Notch signaling in zebrafish	Nature Communications	12.124	2019	RNA-seq
298	Human cell line	Translation of the circular RNA circβ-catenin promotes liver cancer cell growth through activation of the Wnt pathway	Genome Biology	13.214	2019	RNA-seq
299	Monarch butterfly	Transcriptomics of monarch butterflies (Danaus plexippus) reveals strong differential gene expression in response to host plant toxicity, but weak response to parasite infection	bioRxiv		2019	RNA-seq
300	metagenome	Taxonomic and Functional Characterization of the Microbial Community During Spontaneous in vitro Fermentation of Riesling Must	Frontiers in Microbiology	4.076	2019	metagenome
301	Soy	Integration of metabolome and transcriptome analyses highlights soybean roots responding to phosphorus deficiency by modulating phosphorylated metabolite processes	Plant Physiology and Biochemistry	2.718	2019	RNA-seq
302	Human cell line	ZBTB24 regulates the apoptosis of human T cells via CDCA7/TRAIL-receptor axis	Biochemical and Biophysical Research Communications	2.559	2019	RNA-seq
303	yeast	High production of fatty alcohols in Yarrowia lipolytica by coordination with glycolysis	Science China Chemistry		2019	RNA-seq
304	Human cell line	A reference system for BRCA mutation detection based on next-generation sequencing in the Chinese population	JOURNAL OF MOLECULAR DIAGNOSTICS	4.88	2019	capture
305	pig	Transcriptomic analysis of small intestinal mucosa from porcine epidemic diarrhea virus infected piglets	Microbial Pathogenesis	2.332	2019	RNA-seq
306	Human cell line	Nobiletin exhibits potent inhibition on tumor necrosis factor alpha‐induced calcification of human aortic valve interstitial cells via targeting ABCG2 and AKR1B1	Phytotherapy researcch	3.349	2019	RNA-seq
307	Human cell line	Establishment and characterization of a novel childhood acute lymphoblastic leukemia cell line, HXEX-ALL1, with chromosome 9p and 17p deletions	Cancer Cell International	3.96	2019	WGS
308	Human cell line	Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1	Cell Host & Microbe	17.872	2019	RNA-seq
309	Human cell line	Genetic Regulation of enoyl-CoA hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans	DIABETES	7.273	2019	RNA-seq
310	Mouse	Dean flow assisted single cell and bead encapsulation for high performance single cell expression profiling	ACS Sensors	5.711	2019	scRNA-Seq
311	human	Germline-encoded TCR-MHC contacts promote TCR V gene bias in umbilical cord blood T cell repertoire	bioRxiv		2019	MHC capture
312	Muhe	Anticandidal Potential of Stem Bark Extract from Schima superba and the Identification of Its Major Anticandidal Compound	molecule	3.098	2019	RNA-seq
313	Mouse	Rescue of Retinal Degeneration in rd1 Mice by Intravitreally Injected Metformin	frontiers in Molecular Neuroscience	3.902	2019	RNA-seq
314	Pathogen	Clinical value of whole genome sequencing in severe sepsis and cluster nursing intervention	Journal of clinical and Pathological Research(china)		2019	Pathogen detection
315	Pathogen	The application of next-generation sequencing in diagnosing invasive pulmonary aspergillosis:three case reports	American Journal of Translational Research	3.061	2019	Pathogen detection
316	Bovine herpesvirus 1	Cellular microRNA bta-miR-2361 inhibits bovine herpesvirus 1 replication by directly targeting EGR1 gene	Veterinary Microbiology	2.524	2019	Pathogen detection
317	Zebrafish	Estrogen accelerates heart regeneration by promoting inflammatory responses in zebrafish	bioRxiv		2019	RNA-seq
318	umbilical cord blood cell	Single-cell transcriptomic landscape of nucleated cells in umbilical cord blood	GigaScience	7.267	2019	scRNA-Seq
319	Mouse	Short-term High Fructose Intake Reprograms the Transcriptional Clock Rhythm of the Murine Extraorbital	Investigative Ophthalmology & Visual Science	3.388	2019	RNA-seq
320	Human cell line	Sequential treatment failures in response to BRAF/MEK and immune checkpoint inhibitors mediated by MAP2K2 and B2M mutations in melanoma	Experimental and Molecular Pathology	2.566	2019	WES
321	Human cell line	Cancer‐associated fibroblasts contribute to cisplatin resistance by modulating ANXA3 in lung cancer cells	cancer science	4.372	2019	RNA-seq
322	human	Genetic and clinical findings in a large cohort of Chinese patients with suspected retinitis pigmentosa	AMERICAN JOURNAL OF OPHTHALMOLOGY	4.795	2019	WES
323	human	Bismuth drugs tackle Porphyromonas gingivalis and attune cytokine response in human cells	Metallomics	4.069	2019	RNA-seq
324	Mouse	Ferulic acid altered IL-17A/IL-17RA interaction and protected against imiquimod-induced psoriasis-like skin injury in mice	Food and Chemical Toxicology	3.977	2019	RNA-seq
325	Mouse	Alterations in transcriptome and antioxidant activity of naturally aged mice exposed to selenium-rich rice	ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH	2.8	2019	RNA-seq
326	Mouse	Integrated Omics Reveals Tollip as an Aggravator and Therapeutic Target for Hepatic Ischemia‐Reperfusion Injury in Mice	hepatology	13.246	2019	RNA-seq
327	human	Screening, prenatal diagnosis, and prenatal decision for sex chromosome aneuploidy	Expert Review of Molecular Diagnostics	3.326	2019	NIFTY
328	human	Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages	JOURNAL OF CLINICAL INVESTIGATION	13.251	2019	RNA-seq
329	Zebrafish	Loss-of-function of sox3 causes follicle development retardation and reduces fecundity in zebrafish	Protein & Cell	6.228	2019	RNA-seq
330	Rice	A nucleus-localized PPR protein OsNPPR1 is important for mitochondrial function and endosperm development in rice	JOURNAL OF EXPERIMENTAL BOTANY	5.354	2019	RNA-seq
331	Echinococcus	Long-read sequencing reveals a 4.4 kb tandem repeat region in the mitogenome of Echinococcus granulosus (sensu stricto) genotype G1	Parasites & Vectors	3.163	2019	MtDNA sequencing
332	Mouse	Embryoid body-based RNA-seq analyses reveal a potential TBBPA multifaceted developmental toxicity	Journal of Hazardous Materials	6.434	2019	RNA-seq
333	Human cell line	Glutaminyl cyclase inhibitor contributes to the regulation of HSP70, HSP90, actin, and ribosome on gene and protein levels in vitro	JOURNAL OF CELLULAR BIOCHEMISTRY	2.959	2018	RNA-seq
334		Next-Generation Sequencing and Emerging Technologies	SEMINARS IN THROMBOSIS AND HEMOSTASIS	3.345	2019	review
335	palmatum	Comparative transcriptome analysis of genes involved in response to thermal stress and leaf colour change of Acer palmatum	Scientia Horticulturae	1.624	2019	RNA-seq
336	Human cell line	ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development	cell reports	8.282	2019	RNA-seq
337	Rat	Transcriptome profiling of dorsal root ganglia in a rat model of complex regional pain syndrome type-I reveals potential mechanisms involved in pain	Journal of Pain Research	2.645	2019	RNA-seq
338	crab	Transcriptomic analysis provides insight into the mechanism of salinity adjustment in swimming crab Portunus trituberculatus	Genes & Genomics	0.68	2019	RNA-seq
339	virus	Full genome sequence of a novel potexvirus from Euonymus bungeanus Maxim based on RNA-Seq analysis	Archives of Virology	2.16	2019	RNA-seq
340	Mouse	Hepatic Interferon Regulatory Factor 6 Alleviates Liver Steatosis and Metabolic Disorder by Transcriptionally Suppressing Peroxisome Proliferator‐Activated Receptor γ in Mice	hepatology	13.246	2019	RNA-seq
341	actinobacterium	Aeromicrobium endophyticum sp. nov., an endophytic actinobacterium isolated from reed (Phragmites australis)	Journal of Microbiology	2.319	2019	WGS
342	human	Analysis of Normal Tissues Adjacent to the Tumour-specific expressed genes in Breast Cancer	Hereditas(Beijing)		2019	RNA-seq
343	E.coli	Multifaceted Stoichiometry Control of Bacterial Operons Revealed by Deep Proteome Quantification	frontiers in genetics	4.151	2019	RNA-seq
344	Human cell line	The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control	JOURNAL OF EXPERIMENTAL MEDICINE	10.79	2019	RNA-seq
345	Arabidopsis thaliana	mTERF5 Acts as a Transcriptional Pausing Factor to Positively Regulate Transcription of Chloroplast psbEFLJ	molecular plant	9.326	2019	RNA-seq
346	metagenome	Altered respiratory virome and serum cytokine profile associated with recurrent respiratory tract infections in children	Nature Communications	12.124	2019	Pathogen detection
347		SEQdata-BEACON: a comprehensive database of sequencing performance and statistical tools for performance evaluation and yield simulation in BGISEQ-500	bioRxiv		2019	Database&statistical tools
348	Human cell line	Pyroptosis of MCF7 Cells Induced by the Secreted Factors of hUCMSCs	Stem Cells International	3.989	2019	RNA-seq
349	Human cell line	Prospect and challenge of detecting dynamic gene copy number increases in stem cells by whole genome sequencing	Journal of Molecular Medicine	4.938	2019	WGS
350	human	Germline DNA damage repair gene alterations in Chinese prostate patients: More than HRR and MMR	2019 ASCO Annual Meeting Abstracts		2019	WES
351	human	A multi-institutional investigation assessing prevalence of germline genetic alterations in Chinese patients with gastric carcinoma	2019 ASCO Annual Meeting Abstracts		2019	capture
352	Clinopodium chinense	Transcriptome Analysis of Clinopodium chinense (Benth.) O. Kuntze and Identification of Genes Involved in Triterpenoid Saponin Biosynthesis	International Journal of Molecular Sciences	3.226	2019	RNA-seq
353	Mouse	Transcriptional Profiling of Daily Patterns of mRNA Expression in the C57BL/6J Mouse Cornea	CURRENT EYE RESEARCH	2.12	2019	RNA-seq
354	metagenome	Age-dependent sexual dimorphism in the adult human gut microbiota	bioRxiv		2019	metagenome
355	Chlorella	Sequencing and comparative analysis of three Chlorella genomes provide insights into strain-specific adaptation to wastewater	bioRxiv		2019	RNA-seq
356	mouse	Proteomics and Transcriptomics Analysis Reveals Clues into the Mechanism of the Beneficial Effect of Electrical Stimulation on Rat Denervated Gastrocnemius Muscle	Cellular Physiology and Biochemistry	5.5	2019	RNA-seq
357	human	Prenatal Diagnosis of Fetuses with Increased Nuchal Translucency by Genome Sequencing Analysis	bioRxiv		2019	CNV-seq
358	Human cell line	c-Jun Overexpressing CAR-T Cells are Exhaustion-Resistant and Mediate Enhanced Antitumor Activity	bioRxiv		2019	RNA-seq
359	mouse	Interleukin-17 receptor D constitutes an alternative receptor for interleukin-17A important in psoriasis-like skin inflammation	Science Immunology		2019	RNA-seq
360	mouse	Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease	Science Advances	11.511	2019	RNA-Seq&ChIP-Seq
361	mouse	The transcription factor Shox2 shapes thalamocortical neuron firing properties by regulation of key ion channels	bioRxiv		2019	RNA-seq
362	Arabidopsis thaliana	Overexpression of AtAGT1 promoted root growth and development during seedling establishment	Plant Cell Reports	2.989	2019	RNA-seq
363	Human cell line	STYK1 promotes tumor growth and metastasis by reducing SPINT2/HAI-2 expression in non-small cell lung cancer	Cell Death & Disease	5.638	2019	RNA-seq
364	human	A truncating CLDN9 variant is associated with autosomal recessive nonsyndromic hearing loss	Human Genetics	3.93	2019	WGS
365	Pathogen	The diagnostic value of metagenomic next-generation sequencing for identifying Streptococcus pneumoniae in paediatric bacterial meningitis	BMC Infectious Diseases	2.62	2019	Pathogen detection
366	Bacillus thuringiensis	Transcriptome profiling analysis of the intoxication response in midgut tissue of Agrotis ipsilon larvae to Bacillus thuringiensis Vip3Aa protoxin	Pesticide Biochemistry and Physiology	3.44	2019	RNA-seq
367	human	Development of coupling controlled polymerizations by adapter-ligation in mate-pair sequencing for detection of various genomic variants in one single assay	DNA RESEARCH	5.415	2019	long mate pair library
368		Actualités du séquen?age d’ADN-Chroniques génomiques	Med Sci (Paris)		2019	review
369		All Aboard The Genome Exprees: Is a new generation of DNA sequencing technology about to hit the fast track?	Genetic Engineering & Biotechnology New		2019	review
370		Arthropod Genome Sequencing and Assembly Strategies	Insect Genomics		2019	review
371		Clinical metagenomic next-generation sequencing for pathogen detection	Annual Review of Pathology: Mechanisms of Disease		2019	review
372	metagenome	Exploring the human microbiome: The potential future role of next-generation sequencing in disease diagnosis and treatment	Frontiers in Immunology	5.511	2019	review
373	nasopharyngeal carcinoma	FOXA1 reprograms the TGF-β-stimulated transcriptional program from a metastasis promoter to a tumor suppressor in nasopharyngeal carcinoma	Cancer letters	6.491	2019	RNA-seq
374		High-throughput sequencing for the aetiologic identification of viral encephalitis, meningoencephalitis and meningitis A narrative review and clinical appraisal	Clinical Microbiology and Infection	5.394	2019	review
375	Caenorhabditis elegans	Systematic evaluation of C elegans lincRNAs with CRISPR knockout mutants	Genome Biology	13.214	2019	lncRNA
376	Tobacco	Tolerance of Transplastomic Tobacco Plants Overexpressing a Theta Class Glutathione Transferase to Abiotic and Oxidative Stresses	Front. Plant Sci	3.678	2019	RNA-Seq
377	haematococcus pluvialis	Comparative transcriptome analysis of a long-time span two-step culture process reveals a potential mechanism for astaxanthin and biomass hyper-accumulation in Haematococcus pluvialis JNU35	Biotechnol Biofuels	5.497	2019	RNA-Seq&Transcriptome Sequencing
378	Mouse	Identifcation of key genes, pathways, and miRNA/mRNA regulatory networks of CUMS-induced depression in nucleus accumbens by integrated bioinformatics analysis	Neuropsychiatric Disease and Treatment	2.195	2019	RNA-Seq&Small RNA
379	Wallemia mellicola	Genomic Evidence of Recombination in the Basidiomycete Wallemia mellicola	genes	3.191	2019	WGS
380	gastric cancer	LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b	Cancer Cell International	3.96	2019	lncRNA
381	human	A comprehensive assessment of Next‐Generation Sequencing variants validation using a secondary technology	Molecular Genetics & Genomic Medicine	2.695	2019	capture
382	Spodoptera frugiperda	Chromosome level draft genomes of the fall armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae), an alien invasive pest in China	bioRxiv		2019	stLFR
383	human	Differential Roles of the mTOR-STAT3 Signaling in Dermal γδ T Cell Effector Function in Skin Inflammation	cell reports	8.032	2019	RNA-seq
384	Mouse	Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis	Science Translational Medicine	16.71	2019	RNA-seq
385	gastric cancer	Hydroxychloroquine enhances the antitumor effects of BC001 in gastric cancer	International Journal of Oncology	3.333	2019	RNA-seq
386	rice	The nuclear-localized PPR protein OsNPPR1 is important for mitochondrial function and endosperm development in rice	Journal of experimental botany	5.354	2019	RNA-seq
387	virus	Differential expression profiling of lncRNAs related to Epstein‐Barr virus infection in epithelial cells	JOURNAL OF MEDICAL VIROLOGY	1.988	2019	lncRNA
388	Pathogen	Metagenomic Next-generation Sequencing of Cerebrospinal Fluid for the Diagnosis of Central Nervous System Infections: A Multicentre Prospective Study	bioRxiv		2019	Pathogen detection
389		A symbiotic balancing act: arbuscular mycorrhizal specificity and specialist fungus gnat pollination in the mycoheterotrophic genus Thismia (Thismiaceae)	Annals of Botany	3.646	2019	WGS
390	Lotus	Transcription Profiles Reveal the Regulatory Synthesis of Phenols during the Development of Lotus Rhizome (Nelumbo nucifera Gaertn)	International Journal of Molecular Sciences	3.687	2019	RNA-seq
391	Atlantic herring	A chromosome-level assembly of the Atlantic herring – detection of a supergene and other signals of selection	bioRxiv		2019	Hi-C library
392	metagenome	Distinct gut metagenomics and metaproteomics signatures in prediabetics and treatment-na?ve type 2 diabetics	bioRxiv		2019	metagenome
393	lung cancer	Irradiation increases the immunogenicity of lung cancer cells and irradiation-based tumor cell vaccine elicits tumor-specific T cell responses in vivo	OncoTargets and Therapy	2.656	2019	RNA-seq
394	Mouse	Changes in mRNA of liver immune-related genes in obese mice induced by long-term high-fat diet	chinese Journal of cellular and molecular immunology(china)		2019	RNA-seq
395	Pathogen	Diagnosis of osteoarticular tuberculosis via metagenomic next?generation sequencing: A case report	Experimental and Therapeutic Medicine	1.41	2019	Pathogen detection
396	anemone	Combined transcriptomic and proteomic analysis reveals a diversity of venom-related and toxin-like peptides expressed in the mat anemone Zoanthus natalensis (Cnidaria, Hexacorallia)	Archives of Toxicology	5.728	2019	RNA-seq
397	CD4+ T cells	Transcriptome Dynamics Reveals Progressive Transition from Effector to Memory in CD4+ T cells	bioRxiv		2019	scRNA-Seq
398	Chicken	Integrative Analyses of mRNA Expression Profile Reveal the Involvement of IGF2BP1 in Chicken Adipogenesis	International Journal of Molecular Sciences	4.183	2019	RNA-seq
399	human	Muscle-strain injury exudate favors acute tissue healing and prolonged connective tissue formation in humans	FASEB JOURNAL	5.391	2019	RNA-seq
400	Medicago truncatula	MtBZR1 Plays an Important Role in Nodule Development in Medicago truncatula	International Journal of Molecular Sciences	4.183	2019	RNA-seq
401	Lung adenocarcinoma	Lung adenocarcinoma-intrinsic GBE1 signaling inhibits anti-tumor immunity	BMC Genomics	3.501	2019	RNA-seq
402	pig	Comprehensive transcriptomic view of the role of the LGALS12 gene in porcine subcutaneous and intramuscular adipocytes	Molecular Cancer	10.679	2019	RNA-seq
403	human	Delta-like ligand 4/DLL4 regulates the capillarization of liver sinusoidal endothelial cell and liver fibrogenesis	BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH	4.739	2019	RNA-seq
404	Tea Polyphenols	Pathogenic Effects and Potential Regulatory Mechanisms of Tea Polyphenols on Obesity	BioMed Research International	2.197	2019	Small RNA
405	sarcoma	Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma	BMC Cancer	2.933	2019	WES
406	hepar	Hepatocyte TRAF6 Aggravates Hepatic Inflammation and Fibrosis by Promoting Lys6‐ Linked Polyubiquitination of ASK1	hepatology	14.971	2019	RNA-seq
407	human	Clinical diagnosis of single-gene disorders and chromosomal abnormalities based on BGISEQ-500 platform	bioRxiv		2019	capture
408	metagenome	Shotgun Metagenomics of 361 elderly women reveals gut microbiome change in bone mass loss	bioRxiv		2019	metagenome
409	human	Mixed-lineage leukemia protein 2 suppresses ciliary assembly by the modulation of actin dynamics and vesicle transport	Cell Discovery	4.6	2019	RNA-seq
410	Human cell line	Systematic comparison of germline variant calling pipelines cross multiple next-generation sequencers	Scientific Reports	4.01	2019	WGS&WES
411	noroviruses	Replication and transcriptionomic analysis of human noroviruses in human intestinal enteroids	American Journal of Translational Research	3.266	2019	RNA-seq
412	Goose	Endoplasmic Reticulum Stress Marker Gene Grp78 Is Involved in Regulation of Immune/Inflammatory State of Goose Fatty Liver	Acta Veterinaria et Zootechnica Sinica(china)		2019	RNA-seq
413	metagenome	Alterations in the human gut microbiome associated with Helicobacter pylori infection	FEBS open bio	1.959	2019	metagenome
414	human	Expanding the Clinical Spectrum of Osteogenesis Imperfecta Type V: 13 Additional Patients and Review	Frontiers in Endocrinology	3.634	2019	WES
415	Tea	Integrated transcriptomic and phytochemical analyses provide insights into characteristic metabolites variation in leaves of 1-year-old grafted tea (Camellia sinensis)	Tree Genetics & Genomes	1.862	2019	RNA-seq
416	leukocyte	Assessment of the gene expression profiles of leukocytes from different isolations	bioRxiv		2019	RNA-seq
417	carcinoma	Fumaratehydratase-deficient renal cell carcinoma: a clinicopathological and molecular study of 13 cases	Journal of Clinical Pathology	2.346	2019	WGS
418	Yellow Mottle Disease	Identification and Characterization of a Novel Emaravirus Associated With Jujube (Ziziphus jujuba Mill.) Yellow Mottle Disease	Frontiers in Microbiology	4.259	2019	Small RNA
419	Neuroblastoma	Exosomal hsa-miR199a-3p Promotes Proliferation and Migration in Neuroblastoma	Frontiers in oncology	4.137	2019	Small RNA
420	breast cancer	CD137 promotes bone metastasis of breast cancer by enhancing the migration and osteoclast differentiation of monocytes/macrophages	Theranostics	8.063	2019	RNA-seq
421	Human cell line	Fas signaling-mediated TH9 cell differentiation favors bowel inflammation and antitumor functions	Nature Communications	11.878	2019	RNA-seq
422	Arabidopsis thaliana	RAP2.4c and RAP2.4d in the regulation of cold stress and cold priming in Arabidopsis thaliana	REPOSITORIUM DER FREIEN UNIVERSIT?T BERLIN(Germany)		2019	RNA-seq
423	chronic lymphocytic leukemia	Elevated FANCA expression determines a worse prognosis in chronic lymphocytic leukemia and interferes with p53 function	FASEB JOURNAL	5.391	2019	RNA-seq
424	Melanocytes	The Long Noncoding RNA UCA1 Negatively Regulates Melanogenesis in Melanocytes	Journal of Investigative Dermatology	6.29	2019	lncRNA
425	Poncirus trifoliata	Enhanced ROS scavenging and sugar accumulation contribute to drought tolerance of naturally occurring autotetraploids in Poncirus trifoliata	PLANT BIOTECHNOLOGY JOURNAL	6.84	2018	RNA-seq
426	Ancient Mammals	Improving Species Identification of Ancient Mammals Based on Next-Generation Sequencing Data	genes	3.331	2019	WGS
427	metagenome	Compositional and functional features of the female premenopausal and postmenopausal gut microbiota	FEBS LETTERS	2.675	2019	metagenome
428	Pathogen	Genome-wide Transcript Structure Resolution Reveals Abundant Alternate Isoform Usage from Murine Gammaherpesvirus 68	cell reports	7.82	2019	RNA-seq
429	CADASIL	Novel and Recurring NOTCH3 Mutations in Two Chinese Patients with CADASIL	Neurodegenerative Diseases	2.80	2019	WES
430	metagenome	A survey of the sperm whale (Physeter catodon) commensal microbiome	PeerJ	2.35	2019	metagenome
431	nasopharyngeal carcinoma	DHRS2 mediates cell growth inhibition induced by Trichothecin in nasopharyngeal carcinoma	Journal of Experimental & Clinical Cancer Research	5.65	2019	RNA-seq
432	metagenome	Calorie restriction intervention induces enterotype-associated BMI loss in nonobese individuals	bioRxiv		2019	metagenome
433	Scutellaria	The complete chloroplast genome of Scutellaria indica var. coccinea (Lamiaceae), an endemic taxon in Korea	Mitochondrial DNA Part B-Resources	0.561	2019	chloroplast Sequencing
434	Firmiana	Comparative analyses of chloroplast genomes among three Firmiana species: Identification of mutational hotspots and phylogenetic relationship with other species of Malvaceae	plant gene		2019	chloroplast Sequencing
435	Immune Cell	A Single-Cell Immune Atlas of Triple Negative Breast Cancer Reveals Novel Immune Cell Subsets	bioRxiv		2019	scRNA-Seq
436	Candida albicans	Susceptibility to Medium-Chain Fatty Acids Is Associated with Trisomy of Chromosome 7 in Candida albicans	mSphere	4.447	2019	WGS
437	Cancer Cells	Engineering Forward Genetics into Cultured Cancer Cells for Chemical Target Identification	cell chemical biology	6.762	2019	WES
438	zebrafish	Pioneer and repressive functions of p63 during zebrafish embryonic ectoderm specification	Nature Communications	11.878	2019	RNA-seq
439	Monascus	Effects of Different G-Protein α-Subunits on Growth, Development and Secondary Metabolism of Monascus ruber M7	Frontiers in Microbiology	4.259	2019	RNA-seq
440	banana	Characterization of the complete chloroplast genome of Sanming wild banana (Musa itinerans) and phylogenetic relationships	Mitochondrial DNA Part B-Resources	0.561	2019	chloroplast Sequencing
441	kumquat	Characterization of the complete chloroplast genome of the Hongkong kumquat (Fortunella hindsii Swingle)	Mitochondrial DNA Part B-Resources	0.561	2019	chloroplast Sequencing
442	Pedicularis	The complete chloroplast genome of Pedicularis alaschanica (Orobanchaceae)	Mitochondrial DNA Part B-Resources	0.561	2019	chloroplast Sequencing
443	Kuepferia otophora	The complete chloroplast genome sequence of an Alpine flowering plant Kuepferia otophora (Gentianaceae)	Mitochondrial DNA Part B-Resources	0.561	2019	chloroplast Sequencing
444	bacteria	Response of Cupriavidus basilensis B-8 to CuO nanoparticles enhances Cr(VI) reduction	Science of The Total Environment	5.59	2019	RNA-seq
445	Human cell line	RNA-Bloom provides lightweight reference-free transcriptome assembly for single cells	bioRxiv		2019	scRNA-Seq
446	Passiflora edulia Sims	Characterization of the complete chloroplast genome of a purple passion flower variety ‘Pingtang No.1’ (Passiflora edulia Sims) in China and phylogenetic relationships	Mitochondrial DNA Part B-Resources	0.561	2019	chloroplast Sequencing
447	Tetraena mongolica Maxim	De novo transcriptome sequencing and identification of genes related to salt and PEG stress in Tetraena mongolica Maxim	Trees	1.799	2019	De novo transcriptome
448	Nasopharyngeal Carcinoma	Detection and Analysis of RNAs Expression Profile for Methylated Candidate Tumor Suppressor Genes in Nasopharyngeal Carcinoma	Anti-Cancer Agents in Medicinal Chemistry	2.18	2019	RNA-seq
449	colorectal cancer cells	Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells	Journal of Experimental & Clinical Cancer Research	5.65	2019	RNA-seq
450	human embryonic stem cell	Toxicogenomic analyses of the effects of BDE-47/209, TBBPA/S and TCBPA on early neural development with a human embryonic stem cell in vitro differentiation system	Toxicology and Applied Pharmacology	3.585	2019	RNA-seq
451	Lactobacillus casei	A single bacterium restores the microbiome dysbiosis to protect bones from destruction in a rat model of rheumatoid arthritis	Microbiome	10.465	2019	metagenome
452	Gomphonemopsis sieminskae	Morphology and molecular phylogeny of Gomphonemopsis sieminskae sp. nov. isolated from brackish waters of the East China Sea coast	Plant and Fungal Systematics		2019	WGS
453	metagenome	Gut microbiome affects the response to anti-PD-1 immunotherapy in patients with hepatocellular carcinoma	Journal for ImmunoTherapy of Cancer	8.68	2019	metagenome
454	Human cell line	Impact of sequencing depth and technology on de novo RNA-Seq assembly	BMC Genomics	3.501	2019	De novo transcriptome
455	Gerbera jamesonii Bolus	Characterization of the complete chloroplast genome of Gerbera jamesonii Bolus in China and phylogenetic relationships	Mitochondrial DNA Part B-Resources	0.561	2019	chloroplast Sequencing
456	human	Identification of a novel EVC variant in a Han‐Chinese family with Ellis‐van Creveld syndrome	Molecular Genetics & Genomic Medicine	2.448	2019	WES
457	Arabidopsis thaliana	m5C Methylation Guides Systemic Transport of Messenger RNA over Graft Junctions in Plants	current biology	9.193	2019	MeRIP
458	Glioblastoma	Genome‐Wide CRISPR‐Cas9 Screening Identifies NF‐κB/E2F6 Responsible for EGFRvIII‐Associated Temozolomide Resistance in Glioblastoma	Advanced Science	15.804	2019	RNA-seq
459	Haemonchus contortus	Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism	PLoS Pathogens	6.463	2019	RNA-seq
460	Phanerochaete chrysosporium	Sulfadiazine biodegradation by Phanerochaete chrysosporium: Mechanism and degradation product identification	Chemosphere	5.108	2019	RNA-seq
461	mouse	Regulation of the inflammatory response by vascular grafts modified with Aspirin-Triggered Resolvin D1 promotes blood vessel regeneration	Acta Biomaterialia	6.638	2019	RNA-seq
462	Barley	Knockout of the HvCKX1 or HvCKX3 Gene in Barley (Hordeum vulgare L.) by RNA-Guided Cas9 Nuclease Affects the Regulation of Cytokinin Metabolism and Root Morphology	Cells	5.656	2019	RNA-seq
463	tobacco	Expression of AtLEC2 and AtIPTs promotes embryogenic callus formation and shoot regeneration in tobacco	BMC Plant Biology	3.67	2019	RNA-seq
464	insect	Prospects and challenges of implementing DNA metabarcoding for high-throughput insect surveillance	GigaScience	7.27	2019	review
465	soybean	Transcriptomic analysis reveals the possible roles of sugar metabolism and export for positive mycorrhizal growth responses in soybean	Physiologia Plantarum	3.00	2018	RNA-seq
466	periodontitis	M1 macrophages regulate TLR4/AP1 via paracrine to promote alveolar bone destruction in periodontitis	Oral Diseases	2.63	2019	RNA-seq
467	Human cell line	Epigenetic alterations are associated with tumor mutation burden in non-small cell lung cancer	Journal for ImmunoTherapy of Cancer	8.676	2019	WES
468	Chelmon rostratus	Chromosome-level genome assembly of a butterflyfish, Chelmon rostratus	bioRxiv		2019	stLFR
469	Human cell line	Identification of Main Genetic Causes Responsible for Non-Syndromic Hearing Loss in a Peruvian Population	genes	3.331	2019	WGS
470	Human cell line	Bioinformatic Analysis of Transcriptomic Data Reveals Novel Key Genes Regulating Osteogenic Differentiation of Human Adipose Stem Cells	Stem Cells International	3.902	2019	RNA-seq
471	mice	Hyperuricemia is associated with impaired intestinal permeability in mice	American Journal of Physiology-Gastrointestinal and Liver Physiology	3.729	2019	RNA-seq
472	Aspergillus cristatus	Genetic Basis and Function of Mating-Type Genes in Aspergillus cristatus	Mycosphere	1.992	2019	RNA-seq
473	Novosphingobium	Transcriptome Analysis of Novosphingobium pentaromativorans US6-1 Reveals the Rsh Regulon and Potential Molecular Mechanisms of N-acyl-l-homoserine Lactone Accumulation	Int J Mol Sci	4.183	2018	RNA-seq
474	zebrafish	TALE and NF-Y co-occupancy marks enhancers of developmental control genes during zygotic genome activation in zebrafish	bioRxiv		2019	RNA-seq
475	lung cancer	CDYL promotes the chemoresistance of small cell lung cancer by regulating H3K27 trimethylation at the CDKN1C promoter	Theranostics	8.063	2019	RNA-seq
476	Human cell line	Characterizing the Emergence of Liver and Gallbladder from the Embryonic Endoderm through Single-Cell RNA-Seq	bioRxiv		2019	scRNA-Seq
477	Human Herpes Virus	The research between detection of Human Herpes Virus DNA and the prognosis, immune functions of patients with sepsis	Chin J Emerg Med(china)		2019	Pathogen detection
478	Human cell line	Enhance genome editing efficiency and specificity by a quick CRISPR/Cas9 system	bioRxiv		2019	RNA-seq
479	Heortia vitessoides	De novo Analysis of Heortia vitessoides (Lepidoptera: Crambidae) Transcriptome and Identification of Putative Cytochrome P450 Monooxygenase Genes	JOURNAL OF ENTOMOLOGICAL SCIENCE	0.513	2019	De novo transcriptome
480	Mulberry	Physiological and Transcriptomic Changes during the Early Phases of Adventitious Root Formation in Mulberry Stem Hardwood Cuttings	International Journal of Molecular Sciences	4.183	2019	RNA-seq
481	non-small cell lung cancer	Integration of metabolomics and transcriptomics to reveal metabolic characteristics and key targets associated with cisplatin resistance in non-small cell lung cancer	Journal of Proteome Research	3.78	2019	RNA-seq
482	Bactrocera	Azadirachtin A inhibits the growth and development of Bactrocera dorsalis larvae by releasing cathepsin in the midgut	Ecotoxicology and Environmental Safety	4.527	2019	RNA-seq
483	Garlic	Transcriptome Analysis of Low-Temperature-Induced Breaking of Garlic Aerial Bulb Dormancy	International Journal of Genomics	2.303	2019	De novo transcriptome
484	rat	Single xenotransplant of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival	aging cell	7.346	2019	RNA-seq
485	mesenchymal stem/stromal cells	Single-cell RNA-seq highlights heterogeneity in human primary Wharton’s Jelly mesenchymal stem/stromal cells cultured in vitro	bioRxiv		2019	scRNA-Seq
486	human	Three GLI2 mutations combined potentially underlie non‐syndromic cleft lip with or without cleft palate in a Chinese pedigree	Molecular Genetics & Genomic Medicine	2.448	2019	WES
487	metagenome	Fecal microbiota transplantation brings about bacterial strain displacement in patients with inflammatory bowel diseases	bioRxiv		2019	metagenome
488	Human cell line	Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis	molecular cell	14.548	2019	RNA-seq
489	non-small cell lung cancer	Development and Validation of Tumor-educated Blood Platelets Integrin Alpha 2b (ITGA2B) RNA for Diagnosis and Prognosis of Non-small-cell Lung Cancer through RNA-seq	International Journal of Biological Sciences	4.067	2019	RNA-seq
490	Cucurbita pepo	Whole-genome resequencing of Cucurbita pepo morphotypes to discover genomic variants associated with morphology and horticulturally valuable traits	Horticulture Research	3.64	2019	WGS
491	metagenome	Apparent performance of metagenomic next-generation sequencing in the diagnosis of cryptococcal meningitis: a descriptive study	JOURNAL OF MEDICAL MICROBIOLOGY	1.926	2019	metagenome
492	Human cell line	Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses	immunity	21.522	2019	RNA-seq
493		NGS: Gestern, heute und morgen	medizinische genetik (Germany)		2019	review

494	human	Genotyping, generation and proteomic profiling of the first human autosomal dominant osteopetrosis type II-specific induced pluripotent stem cells	Stem Cell Research & Therapy	4.627	2019	WES
495	Mycobacterium tuberculosis	Evaluation of Whole-Genome Sequence Method to Diagnose Resistance of 13 Anti-tuberculosis Drugs and Characterize Resistance Genes in Clinical Multi-Drug Resistance Mycobacterium tuberculosis Isolates From China	Frontiers in Microbiology	4.259	2019	WGS
496	salivary adenoid cystic	Tumor?derived exosomes educate fibroblasts to promote salivary adenoid cystic carcinoma metastasis via NGF?NTRK1 pathway	Oncology Letters	1.871	2019	RNA-seq
497	Staphylococcus	Decreased metabolism and increased tolerance to extreme environments in Staphylococcus warneri during long‐term spaceflight	MicrobiologyOpen	2.738	2019	RNA-seq
498	cervical cancer	REX1 promotes EMT-induced cell metastasis by activating the JAK2/STAT3-signaling pathway by targeting SOCS1 in cervical cancer	Oncogene	6.634	2019	RNA-seq
499	rat	Effects of Bakuchiol on chondrocyte proliferation via the PI3K‐Akt and ERK1/2 pathways mediated by the estrogen receptor for promotion of the regeneration of knee articular cartilage defects	Cell Proliferation	5.039	2019	RNA-seq
500	Pathogen	Incremental value of metagenomic next generation sequencing for the diagnosis of suspected focal infection in adults	Journal of Infection	5.099	2019	Pathogen detection
501	follicular lymphoma	M7‐FLIPI is not prognostic in follicular lymphoma patients with first‐line rituximab chemo‐free therapy	British Journal of Haematology	5.206	2019	capture
502	Penicillium oxalicum	Normal transcription of cellulolytic enzyme genes relies on the balance between the methylation of H3K36 and H3K4 in Penicillium oxalicum	Biotechnology for Biofuels	5.452	2019	RNA-seq